Altruist replied: "Cymbalta can trigger bipolar mania and increase bipolar depression as it works steadily on serotonin. But from what I've heard, you would have more difficulty working with an SSRI antidepressant, than an MRI (multiple reuptake inhibitor) like Cymbalta.
You did not describe the anxiety meds specifically, where the more common type of anxiety meds are benzodiazepines. Regular use of benzodiazepines is know to further increase bipolar depression as well.
It's not uncommon for bipolar patients to attempt suicide (30%). The theory with antidepressants and suicide, is that the individual may have suicidal ideation before taking the meds, but is too depressed to have the motivation to actually do it. Then the antidepressants kick in, the depression dissipates and if the thoughts are prevelent, it becomes easier for the person to follow through on them. It's important that the person be monitored by a Dr. while being prescribed antidepressants for this reason.
In my opinion, the suicidal ideation was probably there way before the Cymbalta. In addition, if suicide or self harm is ever apparent, this person should partake in psychotherapy and not just medication alone."
Random Bloke replied: "Yes, possibly. These meds can all have paradoxical reactions, but the good news is that if the bipolar diagnosis is correct then Lamictal is a fantastic drug (I take it for bipolar)."
If you are taking the antidepressant Cymbalta,are you having difficulty with alot of weight gain? Drowsiness? I've been taking Cymbalta for several months, and WOW, have I packed on the pounds!! Am also very tired, especially mid-afternoon. Anyone else experiencing the same? I often ask myself, "Is it better to be fat and happy? or thin and sad?" HA! If you've gone off Cymbalta for the above reasons, what do you take now? Thanks for your help:)
Trainer & Chemist replied: "The benefits of Cymbalta will really be an individual experience, although these newer drugs tend to carry a lot of benefits and not nearly the amount of side effects as antidepressants in the past. One of the greatest benefits, if Cymbalta works for you, is that it seems to work more quickly than other antidepressants. Many people have to wait eight to sixteen weeks to even begin to feel the effects of any antidepressant. With Cymbalta a good deal of people have begun to see improvement in just a handful of days, or two to three weeks, which is a much more acceptable time frame. This is a huge benefit for people who are suffering from major depressive disorder as they don’t have to waste three to four more months of their life being depressed, if the medication does not seem to be working for them they can try something else.
Relieving depression is a huge benefit to the life of anyone who suffers from major depressive disorder, or any type of depression that his or her doctor deems worthy of medicating. Depression can be as crippling as any physical disease, and stopping or even relieving the extent of the symptoms will be the single best benefit of any drug, including Cymbalta.
For neuropathy pain, just having a medication that helps is a benefit enough. Some people really experience a difference in just a couple weeks, and taking that pain away can really transform a person’s life over night. Cymbalta works to basically marinate your neurons in these brain chemicals, and that helps to relieve pain. Often, when attempting to relieve nerve pain other medications are used in conjunction with Cymbalta to repair nerve tissue to relieve pain both short term and long term. Cymbalta is a very beneficial drug for many people who suffer from the awful nerve pain associated with diabetes and other diseases.
SIDE EFFECTS : dry mouth, nausea, and constipation were experienced as a result of taking Cymbalta. The majority of these patients saw a drastic improvement of the symptoms after fourteen days on Cymbalta, which means their body was just becoming accustomed to the drug. While these are annoying symptoms, they are probably worth getting through for a few days or weeks so that you can improve the quality of your life. Only you can judge whether these are symptoms you can deal with, though they are common of most antidepressants on the market today.
Temporary decreased appetite and weight loss once starting Cymbalta. Insomnia may result from Cymbalta use, or on the flip side you may experience excessive sleepiness or fatigue. Loss of libido and lack of orgasm were also experienced by this small population as well as problems with erection and ejaculation. One to less than ten percent also experienced dizziness, tremor, blurred vision, hot flashes, diarrhea or vomiting. A small percentage of patients also reported increased sweating when taking Cymbalta.
In less than one percentage of men urinary hesitancy occurred as a result of taking Cymbalta. In a minute percent of the population the drug may also cause dilated pupils, and low blood sodium may occur, especially in older people.
If you experience an allergic reaction to Cymbalta such as difficulty breathing, swelling in the throat, or hives you should seek medical attention immediately. You’ll also want to seek medical attention if you experience irregular pulse, low blood pressure often marked by dizziness or weakness, high blood pressure marked by a severe headache and blurred vision, chills or fever, unusual bleeding, or unexplained bruising. These are all more serious reactions and you’ll want to seek immediate medical attention.
Precautions To Consider When Taking Cymbalta :
If you have taken an MAOI type drug such as Marplan, Nardil, or Parnate in the last two weeks you’ll want to wait awhile until you begin to take Cymbalta. The majority of people are not on an MAOI type drug, so it’s likely that is precaution does not apply to you, but if it does you and your doctor should take this warning seriously. Very serious complications often arise when these two types of drugs are mixed, and the complications can be fatal.
You’ll want to mention any drugs that you have been on for the last three to six months before starting Cymbalta. Many people don’t realize that many drugs remain in the system for days or even weeks after they are discontinued, so it’s very important to talk to your doctor and/or your pharmacist to be sure that you will not suffer from any ill-advised drug combinations. While most of what you take will probably not interact adversely with Cymbalta, you should let your doctor or pharmacist decide.
You’ll want to let your doctor know if you suffer from any medical conditions, even if they do not seem to relate to your depression or neuropathy in any way. You’ll especially want to mention kidney or liver disease, diabetes, narrow angle glaucoma, high blood pressure, seizure, bipolar diso"
Does Cymbalta (antidepressant) interfere with Phentermine (diet drug)? I know some Dr.s were doing the Phentermine + Lexapro diet. I did not know how Cymbalta would effect the Phentermine's effectiveness as a diet suppressant..
Your Friendly Jewish Accountant replied: "A diet drug is full of chemicals that mimic amphetamines like meth. If you are actually interested in your mental health, you won't touch the stuff. Tell your doctor you're doing this and watch him hit the roof!"
How to wean myself off of Cymbalta (antidepressant)? I need information as to how to effectively wean myself off of Cymbalta 20mg. an antidepressant. I take one a day, and weigh about 160 pounds (if that has any bearing). I have been taking it for a little over two months now. My therapist doesn't want me to stop taking it, and is not listening to me, so she won't tell me. It's making my depression 100% worse. The doctor just tells me to talk to the therapist. I need to get off of this, and as soon as possible. Please help, as I have talked to the professionals and they will not help me. I've taken it long enough where it should have worked by now, as well. So please, no harping on me. The worsening depression, anxiety, moodiness and other symptoms that have gotten much worse since I started taking this, are interfering with my life, I need off of this. Thank you.
squirrel replied: "start taking it every other day for a few. then every third day for a few. You arent on that high a dose so it shouldnt be too bad. Im on 90 mg- it works for me but if I run out its hell. Just dont stop completely at once! Good luck and I hope you can find something that works better for you."

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